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Category Archive for: ‘Microtubule Stabilizing Agents’

  • Fdiaz

    The Laulimalide tubulin binding site in microtubules unveiled

    The Laulimalide tubulin binding site in microtubules unveiled. Taxane-site MSAs like paclitaxel and epothilones are one of the most successful classes of chemotherapeutic drugs against cancer. However, their clinical application is hampered by toxicity and the development of resistance. The marine sponge products laulimalide and …

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